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A vaccine against skin cancer in phase 3

Auteur: All Buzznews

2024-01-23 08:49:01

The medical community and cancer survivors are eager to see progress in clinical trials of these promising vaccines.

Phase 3

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Under the supervision of Dr. Thomas Wagner, Orbis Health Solutions has developed a vaccine currently in phase 3 clinical trials. This vaccine promises to revolutionize cancer treatment by optimizing the effectiveness of the immune system, while considerably minimizing side effects.

Major advances

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Significant progress has recently been made in the fight against cancer, notably with the emergence of a vaccine treatment that raises hopes of a possible cure for patients suffering from melanoma, a particularly serious form of skin cancer.

Immune therapy

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The vaccine offers an immune therapy designed to boost the body's response against cancer cells. It takes advantage of the body's natural recognition process, teaching it to target cancer cells by identifying them as invaders.

Encouraging results

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Phase 2 clinical trial results for this vaccine were encouraging, in participants with advanced melanoma. The combination of Keytruda treatment and mRNA vaccine demonstrated a significant 49% reduction in the risk of disease recurrence or death, as well as a 62% reduction in distant tumor spread or death at 3-year follow-up. Patients treated with both Keytruda and the mRNA vaccine had significantly lower risks of recurrence and death than those treated with Keytruda alone.

Confirming efficacy

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Around 500 participants will be selected for the start of phase 3 of the clinical trial, in the hope that this more extensive investigation will confirm the vaccine's efficacy.

Side effects

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The vaccine is not only effective, but also has minimal side effects in 75% of patients, mainly injection-site reaction, fatigue and fever. Despite a 25% rate of serious side effects, the treatment profile of Keytruda and the vaccine is considered acceptable...

An acceptable level of risk

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...given the severity of the disease.

A new era?

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The medical community and cancer survivors are enthusiastically anticipating the advent of a new era in cancer therapy. Personalization and immunotherapy could become the foundations of effective treatments, dramatically reducing the severe side effects associated with past treatment.